疏郁安咽汤联合刮痧治疗肝郁脾虚型喉咽反流咽部 异物感患者的临床观察

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[关键词]喉咽反流；肝郁脾虚型；疏郁安咽汤；刮痧；氧化应激；炎症反应 [中图分类号]R276.1 [文献标志码]B [文章编号]doi：10.3969/j.issn.1674-070X.2025.11.013

Clinical observation on Shuyu Anyan Decoction combined with scraping therapy in treating patients with throat foreign body sensation associated with laryngopharyngeal reflux of liver stagnation and spleen deficiency pattern

TAO Xuanran'， WANG Panpan’， ZHANG Zhibo'， GAO Ya'na²， GAO Xiaohong²， DU Xin2* 1.Hebei UniversityofChineseMedicine，Shijiazhuang，Hebei O5ol1，China;2.HebeiProvincial Hospitalof ChineseMedicine，Shijiazhuang，Hebei O5ooll，China

[Abstract]Objective Toobserve theclinicaleficacyof Shuyu Anyan Decoction （SYAYD）combinedwith scraping therapyin treatingpatientswiththroatforeignbodysensationasociatedwithlaryngopharyngealrefluxofliverstagnationandspleen deficiencypattern.MethodsAtotalof8Opatientswiththroatforeignbodysensationassociatedwithlaryngopharygealflux，who weretreatedintheotolaryngologydepartmentofHebeiProvincialHospitalofChineseMedicinefromOctober2O23toOctober 2024，wererandomlydividedintoatreatmentgroupandacontrolgroup，with4Opatientsineachgroup.Ptientsinthetreatment groupreceivedoraladministrationoftheChinesemedicineSYAYDcombinedwithscrapingtherapywhilepatientsintheontrol group weretreated withthe Western medicine OmeprazoleEnteric-coated Capsules.After4 weeksoftreatment inboth groups，The therapeuticeficacyChinesemedicinepaterncoresrefluxsymptomindex（RSIrefluxfindingscore（RFS），uperoxideistase （SOD）levels，andmalondialdehyde （MDA）levelswerecomparedbetweenthetwogroupsbeforeandafter treatment.Results The total effective rate of the treatment group was 92.50% and that of the control group was 75.00% ，with the treatment group's rate being higher than that of the control group （P<0.05 .Aftertreatment， the Chinese medicine pattern scores，RSI scores，RFS scores， and MDA levels in both groups were lower than those before treatment（ P <0.001），with the treatment group exhibiting lower values than the control group （P

[Keywords]laryngopharyngealreflux; liverdepresionandspleendeficiency;Shuyu Anyan Decoction;scraping;oxidative stress；inflammatory response

喉咽反流（laryngopharyngeal reflux disease， LPR）是胃与十二指肠内容物反流至喉咽、口咽甚至鼻咽等部位，这种持续性的酸性及酶类物质刺激可导致咽喉部黏膜出现红斑、水肿等炎症改变，伴随咽部异物感、持续性清嗓、声嘶等特征性临床表现。（剩余6960字）