莲生物碱抗氧化降脂活性及其对植物病原菌的抑菌性能

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关键词：莲（Nelumbonucifera）；生物碱；抗氧化；降脂；抑菌

中图分类号：S482.2；Q946.8 文献标识码：A

文章编号：0439-8114（2025）11-0086-10

DOI：10.14088/j.cnki.issn0439-8114.2025.11.011 开放科学（资源服务）标识码（OSID）：

Investigation of theantioxidantand lipid-lowering activitiesof lotus alkaloidsand their antibacterial propertiesagainstplant pathogens

WANGWen-hao，ZENGYu-ting，YANGZi-jian，LIJing （SchoolofChemistryChemicalEngineringandLifeSiences，WuhanUniversityofTechnology，Wuhan43oina）

Abstract：Asystematicomparatiestudywasconductedtoivesigatetheompositioaldiferencesofalkalodsinlotuslavadlo tusplumules，alongwiththeirespectiveantioxidant，lipid-lowering，andantibacterialproperties.Theanalysisrevealedadistinct compositionalprofile：Alkaloidsinlotusleaveswerepredominantlyoftheaporphine-type，ithnuciferine（otusleafalkaloid）being themostabundant，whilebisbenzylisoquinolinealkaloidswerepredominantinlotusplumules，withnferine（metyllotuspluulealkaloid）havingteighstcontent.Functioall，etotalalkaloidfromlotuslavsebitedsuperiorantioxdantandlipd-lwering activities，demonstratingstrongerDPPHradicalsavengingcapacityandpancreaticlipaseinhibitionbothinaconcentrationdependentmannercomparedtotetotalalkaloidsfromplumule.Inantibacterialassys，theleafalkaloidsalsoshowedmorepotentandsus tainedeiccyinstedomoassngevomto，oondlerriabiStabilityessmnts，weedted thattheantibacterialactivityoftelafalkalodsassusceptibletoighemperatures，inonrasttoehigherteralabilityobserved for the plumule alkaloids.Furthermore，the presence of metal ions （ Ca2+ and Mg2+ ）significantly suppressed the antibacterial activity of both alkaloid types，witha more pronounced inhibitory effectonthealkaloids derivedfrom lotus plumules.

Key Words：lotus（Nelumbo nucifera）；alkaloids；antioxidant；lipid-lowering；antimicrobial

莲（Nelumbonucifera）作为莲科（Nelumbonace-ae）莲属（Nelumbo）的多年生水生草本植物，因其“出淤泥而不染”的高洁形象和优雅的花朵成为观赏佳品。（剩余14618字）