炎症导致老年人贫血的机制研究进展

[Abstract]Anemiaisaprevalenthematologicalcondition，withitsincidencerisingwithage.Inflammationisacrucialfactor thatcontributestoanemia，adverselyfectingredbloodcelltroughiondeficit，diminishederythropoietin（EO）sythesis，decreasedrythropoisis，andincreasedmacrophage-mediatederythrophagocytosis.Furthermore，nflammationmayinducetructural changesinredbloodcelsduetooxidativestressinthebloodstream，leadingtoeightenederythrocytedeathThisreviewdelineates theprimaryproceesviawhichiflammationiducesanmiainteelderlywithteojectiveofenhancingitspreventiondeat ment.

[Key words] Elderly；Anemia；Inflammation；Erythropoiesis；Oxidative stress

世界人口老龄化形势日趋严峻，老年（指年龄 ≥65 岁）群体中，贫血的总体患病率为25%，29% 的住院患者和 54% 的疗养院居民患有贫血[]]老年人贫血按照病因通常分为4种主要类型：营养缺乏性贫血、肾性贫血、炎症性贫血及不明原因性贫血。（剩余10008字）