炎症负荷指数对老年急性ST段抬高型心肌梗死患者经皮冠状动脉介入术后主要心血管不良事件的预测价值
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To investigate the predictive value of inflammatory burden index for major adverse cardiovascular events in elderly patients with acute ST-segment elevation myocardial infarction after percutaneous coronary intervention
Gou Tiantian，Zhang Juan，Liang Jiadong，Liu Tong，Zhang Huan**DepartmentofCardiology，2ndward，theAfiliatedHospitalofNorthwestUniversity，Xi'anNo.3Hospital，Xian1018** Corresponding author： Zhang Huan，email：nojidni258@ 163.com
[Abstract]ObjectiveToinvestigatethepredictivevalueof inflammatoryburdenindex（IBI）formajoradversecardiovascularevents（MACE）afterpercutaneouscoronaryintervention（PCI）inelderlypatientswithacuteST-segment elevationmyocardial infarction（STEMI）.MethodsAtotalof1OOelderlypatientswith STEMIwhounderwentPCIfromJanuary2023toJanuary2024in theDepartmentofCardiovscularMedicie，NorthwesteUniversityAfliatedHospitalwereselectedasthestudysubjectsaddivded into a MACE group （ n=18 ）and a non-MACE group （ n=82 ）according to whether MACE occurred within 6 months after operation. MultivariatelgisticregresionmodelasusedtoanaleteindependentinfluencingfactorsofMACEafterPCIandaROCcuvewas used to analyze the predictive value of IBI for MACE.ResultsThe proportion of patients with ⩾2 diseased vessels in the MACE group was higher than that in the non-MACE group（ P<0.05 ）.N-terminal pro-brainnatriureticpeptide（NT-proBNP），high-sensitivityCreactiveprotein（hs-CRP），cardiacspecifictroponinI（cTnI）andIBIinMACE group were higherthanthoseinthenon-MACEgroup （ P<0.05 ）.Multivariatelogisticregressionanalysiswas performed withtheaboveindicatorsas independentvariables，andtheresults showedthattheumberofseasedesels，N-prBP，s-RP，andwerallidependentisfctorsforAC inelderly STEMI patients（ P<0.05 ）.ROC curve analysis showed that the area under the curve of IBI for predicting MACE was 0.758 （ 95% CI：0.654 toO.862），the sensitivity was0.889，the specificity was 0.610，theYouden index was0.499，and the maximumcut-offvalue as31.495.ConclusionIBIhasa goodabilitytopredictMACEinelderlypatientswith STEMIafterPCIand its highvaluemayindicateahigherrisk ofMACE.
[Key words] ST-segment elevation myocardial infarction；Percutaneous coronary intervention；Inflammatory burden index;
急性ST段抬高型心肌梗死（ST-segmenteleva-tionmyocardialinfarction，STEMI）是心血管疾病中的一种危急情况，通常需要迅速进行冠状动脉介入（Percutaneouscoronary intervention，PCI）治疗以恢复血流[1]。（剩余9045字）
