畜禽基因编辑抗病育种研究进展

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中图分类号：S813.2 文献标志码：A 文章编号：0366-6964（2025）07-3047-10

Abstract： In recent years， gene editing technology has been widely adopted due to its capability for precise and efficient modification of genetic information. By introducing disease-resistant genes or knocking out host genes essential for pathogen infection，this technology can effectively confer resistance to specific infectious diseases in animals，accelerating the development of new livestock and poultry breeds with enhanced disease resistance. Under the threat of major epidemics such as African swine fever （ASF）， there is an urgent need not only to continuously strengthen conventional disease prevention and control measures but also to improve the innate disease resistance of livestock and poultry through genetic breeding. Therefore，cultivating breeds with high-efficiency disease resistance has become a pressing demand and core mission in current animal husbandry research and industrial practices. This paper reviews the current applications of gene editing technology in disease-resistant breeding of livestock and poultry，and prospectively outlines potential future directions and key research areas that warrant focused exploration.

Keywords： gene editing; livestock and poultry; disease resistance; disease resistant breeding

随着我国畜牧业向集约化、规模化方向发展，畜禽养殖密度不断增大，疫病威胁层出不穷。（剩余23920字）