术中肾脏集合系统受损是肾部分切除术后同侧上尿路结石发病的危险因素：一项1：2匹配病例对照研究

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Abstract：ObjectiveToinvestigatetheincidenceofipsilateralupperurinarytractstonesafterpartialnephrectomyanditsrisk factors.Methods Weretrospectivelyanalyzed baseline patient characteristics （age， gender，and body massindex），smoking， alcoholconsumption，comorbidities（hypertension，diabetes，hypertriglyceridemia，hyperuricemia，andcardiovascular diseases），preopeativeorondiions （oriamete，ultilefociation，morhage，osis，sticgsd endophytic growth），preoperative glomerular filtration rate and intraoperative factors （renal colecting system damage， ischemia time，operationtime，surgicalapproachandestimatedintraoperativebloodlosstoidentifytheriskfactors for ipsilateralupper urinarytractstonesfollwingpartialnephrectomyinourcenter.ResultsTheoverallincidenceof upper urinary tract stones following partial nephrectomy was 7.80% （112/1435）. The incidence of ipsilateral upper urinary tract stones was significantlyhigher than those of contralateral stones（ 4.95% Us 1.46% P<0.001 andbilateralstones 4.95% Us 1.39% P<0.001）. Intraoperativedamagetotherenalcollectingsystemwasidentifiedasasignificantriskfactorforipsilateralupperurinarytract stones （OR=4.550， 95% CI： 2.237-9.252， P<0.001 ）.Diabetes wasa probable risk factor for secondary ipsilateral upper urinary tract stones after partial nephrectomy OR=2.419 95% CI： 0.973-6.012， P=0.057 ）. Conclusions The incidence of ipsilateral upper urinarytractstonesafterpartialnephrectomyishigherthanthatofontralateralandbilateralstones.Intraoperativeenal collectingsystemdamageisariskfactorforsecondaryipsilateralupperurinarytractstonesafterpartialnephrectomy. Keywords： partial nephrectomy; urolithiasis; renal collecting system

肾结石（KSD）是泌尿系统常见疾病，其发病率和复发率不断上升。（剩余12746字）