标准化镇静方案在新生儿无创通气（NIV）中的应用效果及对神经发育结果的影响

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Effect of Standardized Sedation Protocol on Neonatal noninvasive Ventilation （NIV） and Its Influence on Neurodevelopmental Outcomes

TENG Fan JIANG Jie （TheSecond People'sHospital ofBaiyin， Gansu Province）

Abstract： Objective： To evaluate the efect of standardized sedation protocol on neonatal non-invasive ventilation （NIV）.Methods： A total of 120 newborns treated in the neonatal intensive care unit （NICU）of the Second People's Hospital of Baiyin， Gansu Province from July 20l9 to July 2024 were selected and divided into the control group and the experimental group，with 6O cases ineach group.Thecontrol group received routine nursing and testing，and the experimental group received standardized sedation. Results： 89% of neonates in the experimental group successfully received non-invasive ventilation support， accounting for a relatively high proportion （P<0.05） . The proportion needing to switch to invasive mechanical ventilation ofthe experimental group was lowerthanthat of the control group （P<0.05） The average score of short-term neurodevelopment in the experimental group was higher than thatinthe control group （ （P<0.05） . At follw-up， the neurodevelopmental scores of the experimental group continued to maintain the superiority （204号 （P<0.05） .Conclusion： Standardized sedation protocol can improve the success rate of neonatal noninvasive ventilation， reduce the need to switch to invasive ventilation，and improve the short-term and long-term neurodevelopmental outcomes of newborns.

Keywords： neonatal non-invasive ventilation; standardized sedation protocol; neurodevelopmental outcome; respiratory management

0 引言

新生儿无创通气（Non-invasiveventilation，NIV）作为一项重要的呼吸支持技术，在新生儿尤其是早产儿的临床治疗中发挥着不可或缺的作用。（剩余3148字）