泮托拉唑、克拉霉素、阿莫西林与果胶铋四联疗法不同疗程治疗胃溃疡临床疗效的比较研究

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中图分类号：R573.1文献标识码：A

DOI：10.3969/j.issn.1006-1959.2025.09.024 文章编号：1006-1959（2025）09-0121-04

Abstract：OetiTploelicalfetfdifntousofdupleappantopleaiomoxiilt pecti）inthetreatfileetdAotalfatsiicedidtifeotyspialof MedicinefromNovember2toNovember223wereseletedanddividedintoroutiegroup34patients）andprolongedgoup34patints）by randomnumbertablemethodBothgoupsweretreatedwithquadrupletherapy（pantoprazole+aritrominamoxicilnisuthpectin）Te conventionalgouastreatedfosdsisfoetialouttesoutedduratioftoled bismuthpectiforeekatioieoftoprazledsmuthtiaseekhcalfcacyptohangsart abdominaldisestetd groups.ResultsThe effectiverateof treatment in the extended group was higher than that inthe conventional group（ P ⋅ <0.05）.After treatment， the symptomscoreseartbubdominaldistesioausea）oftheogroupswerelowrtantosebeforetreatmentandthesptoore （heartburn，abdominal distension，nausea）of theextended groupwere lower than those of the conventional group（ P<0 . 0 5 ）.The gastric ulcer healing timeintheeteddgoassoreranthatinoeoaloudecteasowrantatintoetialou P< （204号 0.05）.There was no significant diference in the incidence of adverse reactions between the two groups（ ）.Conclusion Quadruple therapy （pantoprolilitfsnt andbismuthtisisiataleotofseleat of the disease，reduce therisk ofrecurrence of gastric ulcer，and donot increase theadverse reactions of patients.

Key words：Gastric ulcer： Quadruple therapy; Pantoprazole; Clarithromycin; Amoxicillin; Pectin bismuth

胃溃疡（gastriulcer，GU）为消化内科常见疾病，多由幽门螺杆菌（Helicobaeterpylori，Hp）感染等原因引起的胃黏膜损伤所致，常伴有胃灼烧痛、腹胀、恶心等症状，若未及时治疗，可导致胃穿孔、出血等不良后果，对患者生存健康构成了较大威胁[。（剩余4790字）