褪黑素与针灸治疗早发性卵巢功能不全的疗效及对血清性激素、卵巢动力学的影响

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中图分类号：R711.5文献标识码：A

DOI：10.3969/j.issn.1006-1959.2025.09.021 文章编号：1006-1959（2025）09-0110-04

Abstract：ObjectiveTalyturatieectofelatoombinedithcupuctureandoibustiointhreatmentofprematuan insufcienc（O.MethdsAtalof68patientsihOdmitedtoourospialfromJune2toJune23weredividedtoobind groupandcontrolgroupbyrandomnumbertablemethod，with84patientsineachgroup.Tebasictreatmentofthewogroupswashoone replacementherapyTecontrolgroupwasreatedwithacupunctureandmoxibustiononthisbasis，whiletheombinedgroupwastreatedwith melatonintablesosisofotrou.halfacosstrdiol）eooli stimulating）talt）aeadoe [ovarianeyiyiatli（d groups.Results After treatment， the levels of AMH，AFC，pregnancy-related protein level，EDV，and PSV inboth groups were higher than before treatment，and those in the combined group were higher than those in the control group（ P<0 . 0 5 ） . After treatment，LH，FSH，PI，andRI inboth groups were higher than before treatment，and those inthe combined group were lower than those in thecontrol group（ P<0 . 0 5 ） .Conclusion Melatonin combinedwithcuuncueadoxbustioisetieinereamntofOichcanpoeuseoontrallet pregnancy-related protein and ovarian hemodynamics，and further improve ovarian function.

Key words： Premature ovarian insuficiency; Melatonin; Acupuncture and moxibustion; Hormone replacement therapy

早发性卵巢功能不全（premature ovarian insuf-ficiency，POI）病因复杂多样，据报道，我国POI发病率为 ，不同于正常女性的自然绝经，POI不仅影响女性生育力、心理健康，且对POI患者骨骼、心血管、泌尿生殖系统等健康造成不良影响。（剩余6074字）