基于浊毒理论探讨难治性痛风病机及诊疗思路

[中图分类号］R589 [文献标志码］A [文章编号]0256-7415（2025）14-0157-04

DOl：10.13457/j.cnki.jncm.2025.14.030

Exploration the Pathogenesis and Diagnostic-Therapeutic Approaches for Refractory Gout Based on Turbid Toxin Theory

HU Xinru1.2，WANG Haiyan1.²，XU Lingying 1，2 ，GUO Qihong 1，2 ，ZHENG Baolin 1，2 （20 1.Guangzhou UniversityofChineseMedicine，Guangzhou Guangdong5106，China；2.Foshan Hospitalof Traditional Chinese Medicine，Foshan Guangdong 5280oo，China

Abstract：Refractory gout （RG）is characterized by a prolonged course，persistent difficulty in healing，and numerouscomplications.Due to isues with patient treatment adherence，modern medicine has shown limited efficacy in treating RG.The turbid toxin theoryshares many similarities with the pathogenesisofRG.Guided by the turbid toxin theory，this studyanalyzes the etiologyand pathogenesis ofRGand proposes treatment principles forthree syndromes ： imbalanceof clearand turbid，toxic pathogen atacking thecollaterals，and comorbidityof turbidand toxin.The study explores the application of rattan medicinals and stone-expeling medicinals，flexible prescription selection，syndrome diffrentiation，and symptom-based modifications， providing new clinical treatment approaches for RG.

Keywords：Refractory gout；Turbid toxin theory；Etiologyand pathogenesis；Rattn medicinals； Stoneexpelling medicinals

痛风是由尿酸单钠晶体在关节和周围组织中沉积所引起的一种炎症性关节炎，与血清中尿酸水平升高的高尿酸血症直接相关，其特征是受影响关节反复出现红肿热痛和功能障碍。（剩余5840字）