腹腔镜胰十二指肠切除术后胰瘘危险因素分析

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DOI：10.16424/j.cnki.cn32-1807/r.2025.05.011

[中图分类号]R735.7 [文献标志码]A [文章编号] 1674-7887（2025）05-0462-04

Analysisof risk factors forpancreatic fistula after laparoscopic pancreaticoduodenectomy* CHEN Jie**，LU Zefa， ZANG Hong*** （Department of Hepatobiliary and Pancreatic Surgery， the Second Affiliated Hospital of Nantong University， Jiangsu ）

[Abstract]Objective：Toanalyzetheriskanditsinfluencingfactorsofpancreaticfistulaafterlaparoscopicpancreaticoduodenectomy（LPD）.Methods：：Theclinical dataof49 patientsunderwentLPDinthe HepatobiliaryPancreatic Surgery Departmentof the SecondAfiliated Hospitalof Nantong Universityfrom January2O2O to January2O24 wereretrospectively analyzed.Theincidenceofpancreaticfistulainpatientswasanalyzed.Therisk factorswereanalyzedusingunivariateand multivariate methods.Results：The incidence of postoperative pancreatic fistula in 49 patients was 24.5% .Univariate analysis showed that： BMI≥25 kg/m²， bilirubin levels ⩾150 mmol/L， soft pancreatic texture，pancreatic duct diameter≤3 mm， albumin levels ⩽ 35 g/L ，and the use of pancreatic stents were risk factors for postoperative pancreatic fistula inLPD patients.Logistic regresion analysisrevealedthat soft pancreatic texturewasan independentrisk factor for pancreatic fistula after surgery. Conclusion：The textureof thepancreas isrelated topancreaticfistulaafterLPDsurgeryAdoptingpersonalizedsurgicaland perioperative management strategies can help reduce the occurrence of pancreatic fistula and improve prognosis.

Keywords]laparoscopic pancreaticoduodenectomy; risk factor; pancreatic fistula

胰十二指肠切除术是肝胆胰外科复杂且具有挑战性的手术，主要用于治疗位于胰头、胆管远端及壶腹部的肿瘤等疾病。（剩余4624字）