白蛋白校正阴离子间隙对老年糖尿病酮症酸中毒患者预后的预测价值

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[Abstract]ObjectiveTo explore the predictive value of albumin corected anion gap（ACAG）forthe prognosis of elderly patientswithdiabeticketoacidosis.MetodsAtotalofOOelderlypatientswithdiabeticketoacidosisadmitedtoSengingHospital AffiliatedtoChinaMedicalUniversityfromMay2O22toJune2O24wereselectedastheresearchsubjects.Thegender，age，body mass，height，durationofdiabetes，typeof diabetes，aniongap（AG），albumin（Alb），glycatedhemoglobin（HbAlc），fasting blood glucose（FBG），blood ketone bodies（BK），urine ketone bodies（UK），arterial blood pH value，bloodbicarbonate （ HCO3- ），and neutromidsof10Opatients werecollectedThelevelsofcells（NEU）andlymphocytes（LYM），body massindex，the ACAGand neutrophil-to-lymphocyteratio（NLR）werecalculated.Onehundred patientswerefollwedupcontinuouslyfor28days. Acording to theprognosisandsurvivalstatusofthepatients，theyweredividedintothesurvival group（7lcases）andthedeathgroup （29cases）Throughunivariateandmultivariatelogisticregresionanalyses，therisfactorsforporprognosisinelderlypatntswith diabetic ketoacdosis ere explored，andthepredictiveeficacyof ACAGforporprognosis wasevaluatedusingthereceiveroperating characteristiccurve（ROC）curve.ResultsTheresultsof univariate analysisshowedthat thelevelsof AG，ACAG，HbAlc，NEU and NLRinthe death groupwere all higher thanthoseinthe survival group（ P<0.05 ），andthelevelsofAlb andLYMwerelower than those in the survival group （ P<0.05 ）The results of multivariate logistic regression analysis showed that the levels of AG，ACAG， and HbAlc were risk factors for poor prognosis （ ⋅P<0.05 ），while thelevel of Alb was aprotectivefactor （ P<0.05 ） . ROC curve analysisshowedthattheareasunderthecurveofAG，Alb，ACAGandHbAlcforpredictingporprognosisinelderlydiabeticketoacidosis patients were0.757，0.765，0.814and0.771，respectively，ACAG had thehighest predictivepower.ConclusionACAG hasa 王思萌，等.白蛋白校正阴离子间隙对老年糖尿病酮症酸中毒患者预后的预测价值 highvalueinpredictingteprogosisofelderlypatintsithdabeticketoacidosisandiscommendedfocicalpromotionadaplication.

[Keywords] Albumin corrected anion gap；Diabetic；Ketoacidosis；Prognosis；Predictive value

糖尿病是一种慢性代谢病，起因于胰岛素分泌不足或功能受损，其发病率在我国及全球均较高[1。（剩余8459字）