氨茶碱与甲泼尼龙琥珀酸钠联合治疗慢性阻塞性肺病急性 加重期的临床效果及对血清CRP水平、 PaO2 的影响

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关键词:氨茶碱;甲泼尼龙琥珀酸钠;慢性阻塞性肺病急性加重期;CRP; PaO2 中图分类号:R563 文献标识码:A
DOI:10.3969/j.issn.1006-1959.2025.13.030 文章编号:1006-1959(2025)13-0150-04
Abstract:OectieTexplotlcalofmioyineobdielpredsoloesodmsucateintreafte exacerbation of chronic obstructive pulmonary disease and its effect on serum CRP level and PaO2. Methods A total of 6O patients with acute exacerbationofronctructiepulmoardseaseadmitedtoYushanCountyHuanisiHospitalfroMa1toMa24weeeletd theresearcectscodingtoeadomumberablemetod,teyeredvidedintocontrolgounddyoup,ith3Opatitsc group.Thecotroloupastreaedwitnohlnendtesdopsreadwitethlpredsoloeucateoef thecontrolgoiddiaiti capacityinthefirstsecondtoforcedvitalcapacity(FEV/FCV),seruminflammatoryfactorlevels[tumornecrosisfactor ∇⋅α∝ (TNF-α),interleukin-8 (IL-8),procalcitonin (PCT),C-reactive protein (CRP)], blood gas index levels ⌊pH ,arterial partial pressure of carbon dioxide (PaCO2),arterial partial pressure of oxygen (Pa02)- werecomparedbetweenthetwogroups.ResultsThetotalefectiverateof treatmentinthestudygroupwashigherthan that in the control group( P<0.05) .Thelung function indexes of the study group were better than those of the control group( P<0.05) .Thelevelsof serum inflammatory factors in the study group were lower than those inthe control group( P<0.05) .The level of PaCO2 in the study group was lower than that in the control group,while the level of PaO2 was higher than that in the control group (P<0.05) .Conclusion The combination of aminophyllneandethlpredisolosoduciateasadefinitecliicalectitetrmentofpatintsitacueeacbationf chronicobstructivepulmonarydiseasehichcanimprovetheungfuctionofpatients,educetheilammatoryesponseofpatientspoe the clinical effectand bloodgasindexlevel,andisworthyof clinical application.
Keywords:Aminophyline;Methylprednsolonesodiumsuinate;Acuteexacerbationofchronicobstructivepulmonarydisease;CRP; PaO2
慢阻肺(chronic obstructive pulmonary disease,COPD)在临床中极为常见。(剩余5654字)