阿奇霉素联合布地奈德雾化治疗小儿支气管肺炎的效果及对患儿临床症状的影响

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中图分类号：R725.6 文献标识码：A DOI：10.3969/j.issn.1006-1959.2025.13.020

文章编号：1006-1959（2025）13-0108-05

Abstract：ObjectieTivestigatethefctofaiomincombinedwithbudesodeatozationietreatmentofroopoan childrenadistocalstosetosFroFartogstdatrisiocopod ShanggaoCountyatealandCildHealthHospitalereeoledndandomlyloatedintoseatiogoup（=3ndotroloup n= 30）.Tecontroodioothayleaioouevedoloitdedlcal eficacyhesapaanceficalostasapprancieiciouhanedlngale disappearance）aokese6ter88）osildci protein（CRP）]duoaryfctiorameersdvialpacityC）edxpiatooueiescodEV）aiao flow （PEF），maximum mid-expiratory flow rate （MEF 25-75） ，and forced expiratory flow rates at 50% （ MEF50 and 25% （ MEF25） ] were compared between the groups.Results The total effective rate of treatment in the observation group （96.67 % ）washigher than that in the control group （73.33 % ） P< 0.05）.Cmparedithhtroloutsaeaaeflaltossuchsaapparaeintietiiou disappearance time and lung rale disappearance time in the observation group were shorter （ P<0.05 ）.The levels of inflammatory factors（IL-8，IL-6， TNF- αα∝α ，CRP）inthetwogroupsaftertreatmentwerelowerthanthosebeforetreatment，andcomparedwiththecontrolgroup，thelevelsof inflammatoryfactors（IL-8，IL-6，NF- ∇⋅α∝α. ，CRP） in the observation group after treatment werelower（ P< 0.05）.The levels of lung function indexes（FVC， FEV1 PEF，MEF 25⋅ MEF 50⋅Φ MEF25-75 in the two groupsafter treatment were higherthan those before treatment，and compared with the control group， the levels of lung function indexes（FVC， FEV1 ，PEF，MEF 25 ，MEF 509 MEF 25-75 ）in the observation group after treatment were higher（ P <0.05）. ConclusionAzithomycincombinedwithudesonideatomzaionisfectiveintetreatmentofbrochopemoia，whichcanshortethe disappearance timeofclinical symptoms，reduce inflammatoryreactionandimprovelungfunction.Itisworthyofclinicaluse.

Key Words：Azithromycin; Budesonide;Atomization therapy; Bronchopneumonia; Lung function

支气管肺炎（bronchopneumonia）是由支原体、病毒、霉菌、细菌等多种病原体导致的一种呼吸系统疾病，其中混合感染的情况也时有发生，通常在春季和冬季发病率较高。（剩余6823字）