清开灵注射液治疗急性脑梗死合并肺炎的临床研究

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[Abstract]Objective：To explore theclinical efect of Qingkailing Injection on patients with acute cerebral infarction complicated with pneumonia.Method： Sixtypatients with acutecerebral infarction complicated with pneumonia admited to Jiangxi Provincial People's Hospital from June 2O23 to February 2024 were selectedas the study objects and divided into control group （n=29） and treatment group （ n =31）according to the treatment methods. The control group was routinely treated with antibiotics for anti-infection and symptomatic supportive therapy，on this basis，the treatment group was additionaly treated with Qingkailing Injection.The treatment cycle for both groups were 10 to 14 days.The therapeutic effcts， WBC， neutrophil （N）， CRP， modified Rankin scale （mRS） scores， NIHSS scores，time for body temperature to return to normal， hospital stay and adverse reactions of the two groups were compared.Result： The total effective rate of the treatment group was 90.3% ，whichwassignificantlyhigher than 62.1% of the control group（ P <0.05）.After treatment， the pneumonia score，WBC，N， CRP，mRS score and NIHSS scores of the treatment group were lower than those of the control group （ P <0.05）. There was no statistically significant difference in the incidence of adverse reactions between the two groups （ P>0.05 ）.Conclusion：The effect ofQingkailing Injection combined withantibioticsinthe treatmentof acute cerebral infarction complicated with pneumonia is significantly better than that of using antibiotics alone.

[Keywords] Acute cerebral infarction Pneumonia Qingkailing Injection Anitbiotics

First-author's address： Department of Neurology，Jiangxi Provincial People's Hospital， Nanchang 330006， China

doi：10.3969/j.issn.1674-4985.2025.23.030

急性脑梗死占我国脑卒中的 69.6%～70.8% ，通常起病急骤，并迅速出现不可逆转的脑功能障碍[-2]。（剩余6032字）