替罗非班序贯双重抗血小板治疗对急性 缺血性脑梗死患者预后的影响

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[Abstract]Objective： To explore the application efectof Tirofiban sequential dual antiplatelet therapy in acute ischemiccerebral infarction.Method：Aretrospectivestudy was conducted on 64 patients with acute ischemic stroke treated in the Departmentof Neurologyof HulunbuirPeople's Hospitalfrom January 2O23 to January 2024. The patients were divided into groups based on whether Tirofiban was included in their treatment. The control group （32 patients）receiveddualantiplatelettherapywith ClopidogrelandAspirin，whiletheobservation group（32patients） received Tirofibansequentialdualantiplatelettherapy.Theefcacy，neurological function，degreeofdisabilityand incidenceof adverse reactions were compared betweenthe two groups.Result：The total efectiverateof theobservation group was higher than that of the control group （P<0.05） . After 3O d of treatment， the NIHSS score and mRS score in the observation group were lower than those in the control group P<0.05） .There was no significant difference in the rate of adverse reactions between the two groups （ P>0.05 ）. Conclusion： Tirofiban sequential dual antiplatelet therapy demonstrates confirmed effcacy and favorable safety in the treatment of acute ischemic cerebral infarction.

[KeyWords]Acute ischemic cerebral infarction Tirofiban Sequential therapyDual antiplatelet therapy leurological function

First-author'saddress：Departmentof Neurology，Hulunbuir People'sHospital，Hulunbuir021000， China doi：10.3969/j.issn.1674-4985.2025.23.028

急性缺血性脑梗死不仅治疗难度大，且潜在的致残、致死风险较高[]。（剩余4880字）