针刀在慢性疼痛治疗中的作用机制研究进展

Research Progress on the Role of Acupuncture Knife in the Treatment of Chronic Pain/HE Shuqi， CHENG Ling，XIONGWei，LAI Yunmei，ZHOU Ziyan，PENGTianzhong.//Medical Innovationof China， 2025，22（18）： 183-188

[Abstract]Chronic painhas a profound impact on patients'daily lives and has become one of the main causes of global health problems.Acupotomytherapyplaysan importantroleinthetreatmentofchronicpain.This study aims to explore the mechanism of action of acupotomy in thetreatment ofchronic pain.A comprehensive analysis of relevant literatures in the past1O years has found that acupotomycan alleviate pain by regulating the release of neurotransmittrs，regulating the expression of inflammatoryfactors，inhibiting the processofcell apoptosis， and affecting specific signaling pathways.These studiesprovidea theoretical basisfor the clinical application of acupotomy in the treatment of chronic pain and ofer directions for in-depth research on the mechanism of acupotomy in the treatment of chronic pain in the future.

[Keywords] Acupuncture Chronic pain NeurotransmittersInflammatory factorsApoptosis Signaling pathways

First-author'saddress：Graduate School of Jiangxi Universityof Traditional Chinese Medicine， inchang 330004， China doi：10.3969/j.issn.1674-4985.2025.18.041

慢性疼痛是一种复杂且普遍存在的疾病，涵盖了持续时间长、影响深远等多方面的疾病特性。（剩余12248字）