基于“脾肾阳虚，痰浊阻滞”理论探讨神经根型颈椎病与线粒体自噬的关系

Exploring the Relationship between Cervical Spondylotic Radiculopathy and Mitophagy Based on the Theory of "Yang Deficiency of Spleen and Kidney， Blockade of Phlegm-Turbidity"/WANG Yue， DONG Ping，YAO Guangyuan， HU Kai. //Medical Innovation of China， 2025， 22（12）： 180-184

[Abstract]The pathogenesis and treatment of cervical spondylotic radiculopathy are the focus of medical research at present.Mitophagy is the process of removing or degrading damaged and aged mitochondrion. Mitophagy plays an important role in the occurrence and development of intervertebral disc degenerative change and neuropathic pain， and both intervertebral disc degenerative change and neuropathicpain are closely related to cervcal spondylotic radiculopathy，so it is inferred that mitophagy is closely related to the onset of cervical spondyloticradiculopathy.According totraditional Chinesemedicine， the main pathogenesis ofcervical spondylotic radiculopathy is yang deficiency of spleen andkidney and blockade of phlegm-turbiditywhich is similar to mitophagy atthe microscopic level.Therefore，based on the theory of "Yang deficiency of spleen and kidney， blockade of phlegm-turbidity"，this paper willexploretherelationshipbetween mitophagy andcervical spondylotic radiculopathy fromthe perspective of traditional Chinese medicine and western medicine，providing anew direction and target for the research and treatment of cervical spondylotic radiculopathy.

[Key words] Cervical spondylotic radiculopathy Yang deficiency of spleen and kidney Blockade of phlegm-turbidityMitophagy

First-author's address： College of Traditional Chinese Medicine， Inner Mongolia Medical University， Iohhot 010110， China

doi：10.3969/j.issn.1674-4985.2025.12.043

神经根型颈椎病（cervical spondylotic radiculopathy，CSR）占颈椎病的 60%～70% ，是颈椎及其附属结构退变压迫神经根出现颈部不适，伴有上肢放射痛与麻木的常见颈椎病，严重影响患者的身心健康。（剩余8726字）