HER2阳性乳腺癌治疗的研究进展

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Research Progress in the Treatment of HER2-positive Breast Cancer/FAN Xuejiao， WU Tao， YUAN Ye.//Medical Innovation of China， 2025， 22（11）： 184-188

[Abstract]HER2-positive breast cancer is a highly aggressive tumor subtype， and its treatment strategies have beenahot topic inthe fieldof cancer research and haveundergone significant changes in thepastfew decades. With the in-depth understanding of HER2-positive breast cancer， treatments for HER2-positive breast cancer are continuously innovating，significantly improving thesurvival prognosis of patients.This article reviewsthe latest research progress in the field of HER2-positive breast cancer treatment， including the development of targeted drugs， immunotherapy， cell therapy， and new drugs.

[Key words] HER2-positive breast cancer Targeted therapy Immunotherapy Treatment strategy

First-author's address： Department of Breast Surgery One， Affliated Tumor Hospital of Xinjiang Medical University， Urumqi 830ooo， China doi ： 10.3969/j.issn.1674-4985.2025.11.041

人表皮生长因子受体2（HER2）阳性乳腺癌占所有乳腺癌患者的 20%～30% ，其特点是HER2基因扩增和蛋白过表达，与疾病的恶化和预后不良密切相关-]。（剩余10182字）