溃疡性结肠炎致骨质疏松症的发病机制研究进展

[Abstract]Ulcerativecolitis（UC）isaprevalentinflammatory boweldiseasethatisassociated with multiple systemiccomplications.Withthegrowingaging populationinChina，theprevalenceofosteoporosis（OP）hasreachedthe highestlevelworldwide. UCcanleadtosecondarypathologicalchangesthatdisruptskeletalhomeostasisandreducebonemineraldensity，therebysignifiantly increasingtheriskofOPinfectedpatients.ThisreviewexplorestheunderlyingmecanismsofUC-inducedOP，includingmicronutrientdeficiencyidativess，fmtoysones，nditestialcoaldiosismmagentols article alsoaims to provide atheoretical foundation for the preventionand management of OP in patients with UC.

[Key words] Ulcerative colitis；Osteoporosis；Pathogenesis mechanism；Bone density

溃疡性结肠炎（Ulcerativecolitis，UC）是临床上一种常见的炎症性肠病，主要见于乙状结肠、降结肠、直肠，严重时可累及全结肠。（剩余10894字）