瑞马唑仑与丙泊酚对老年腹腔镜手术患者麻醉诱导期血流动力学及术后认知功能的影响

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[Abstract]ObjectiveTo investigatetheefectsof RemazolamandPropofolonhemodynamicsand postoperativecognitive functionduringanesthesiainductioninelderlypatientsundergoinglaparoscopicsurgery.Methods116elderlypatientsundergoingelectivelaparoscopicsurgeryinYibinHospital，WestChinaHospitalSichuanUniversityfromDecemberO22toMarch4were lectedasthestudysubjectsanddividedintoobservationgroupandcontrolgroupacordingtorandomnumbertable，with58casesin eachgroup.Remazolamwasusedforanesthesiainductionandmaintenanceintheobservationgroup，andPropofolwasusedforanesthesianductionandmaintenanceinthecontrolgroup.Thehemodynamicindicatorsandthequalityofrecoveryattwodierenttime points werecompared，andtheoccurrnceofadversereactionsandcognitivefunctionscoreswererecorded.ResultsIntheobservationgroup，thehartateandmeanarterialpressureimmediatelyaftertrachealintubationand3minafterintubationwerehigherhan those in the control group （ P<0.05 ），the spontaneous respiratory recovery time，eye-opening time and extubation time were shorter thanthose in thecontrol group（ P<0.05 ），thecognitive function scores at1d and3d after operation were higher than thosein the control group （P<0.05 ），the total incidence of adverse reactionswaslower than that in thecontrol group（ P<0.05 ）.Conclusion ComparedwithPropofol，Remazolamisusedinelderlylaparoscopicsurgery，withmorestableintraoperativebloodflowfluctuations， fasterpostoperativerecoveryndfewradverseeactions.Forpatientswithlsscognitivefunctio，itisstablefolderlypatits withrelativelyweak bodyand easilyunstable hemodynamics.

[Key words] Remazolam；Propofol；Laparoscopic surgery；Hemodynamics；Cognitive function

腹腔镜手术是临床常用手术方法，全麻手术在老年患者中的应用越来越普遍[1]。（剩余8812字）