骨肿瘤病人肌少症发生现状及影响因素

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Status quo and influencing factors of sarcopenia in patients with bone tumor

YU Jun1， CHEN Yanyu1， CHEN Jian1*， LU Yulin2， ZHANG Lin1， YOU Shaomei1

1.Peking University Cancer Hospital Yunnan Hospital/Yunnan Cancer Hospital/The Third Affiliated Hospital of Kunming Medical University， Yunnan 650118 China； 2. Yunnan Medical and Health Vocational College

*Corresponding Author  CHEN Jian， E⁃mail： 17697315@qq.com

Abstract    Objective： To analyze the current status and influencing factors of sarcopenia in patients with bone tumors and to provide a reference for developing effective intervention programs.Methods：Using a convenience sampling method，198 patients with bone tumors admitted to the orthopedics department of a tertiary grade A hospital in Yunnan province between August 2023 and January 2024 were recruited.Clinical data were collected， and muscle strength（grip strength），physical activity capacity（walking speed），and muscle mass（appendicular skeletal muscle index） were measured. Patients were assessed using the Patient⁃Generated Subjective Global Assessment，Kinesiophobia Scale⁃Short Form，Fried Physical Phenotype Frailty Scale， and Athens Insomnia Scale.Multivariate Logistic regression analysis was conducted to identify the influencing factors of sarcopenia in patients with bone tumors.Results：The incidence of sarcopenia among patients with bone tumors was 27.27%. Logistic regression analysis revealed that body mass index（BMI），regular exercise，osteoporosis，kinesiophobia，and frailty were significant influencing factors of sarcopenia in patients with bone tumors（P<0.05）.Conclusion：The prevalence of sarcopenia is high in patients with bone tumors. Healthcare professionals should promptly identify high⁃risk groups for sarcopenia and implement nutritional，exercise，and psychological interventions to improve patient outcomes.

Keywords    bone tumor； sarcopenia； influencing factors； exercise intervention； psychological intervention； nutritional support； investigation and study

摘要  目的：分析骨肿瘤病人肌少症发生现状及影响因素，为制定有效的干预方案提供参考。（剩余11274字）