动物皮肤伤口愈合的分子机制与创新治疗策略

打开文本图片集

中图分类号：S857.5 文献标志码：A 文章编号：0366-6964（2025）09-4267-12

Molecular Mechanisms and Innovative Therapeutic Strategies for Cutaneous Wound Healing in Animals

YU Shilong，YUE Xiaoyu，LUAN Yue，WANG Qin* （College of Animal Science and Technology，China Agricultural Uniuersity， Beijing 100193，China）

Abstract： Skin wound healing is a complex physiological process involving inflammation，tissue regeneration，and extracellular matrix remodeling. Dysregulation of this process can lead to excessive scarring or chronic ulcers，impairing skin function. This review summarizes the molecular mechanisms underlying wound healing in animal skin and explores various repair strategies，including novel drug development， enhanced drug delivery， regulation of hormones and external signals，gene therapy，and tissue engineering approaches. These methods improve wound healing outcomes by optimizing drug delivery，modulating inflammatory responses，and promoting vascularization and tissue regeneration. This study aims to provide new insights into animal skin wound healing，highlight potential research directions，and contribute to the development of safer and more effective therapeutic strategies to enhance animal health and welfare.

Keywords ： animal welfare; skin trauma;wound healing；molecular mechanisms； therapeutic approaches ∗ Corresponding author： WANG Qin，E-mail ： wangqin@cau. edu. cn

在现代畜牧业和伴侣动物产业中，动物的皮肤健康不仅关系到其生活质量，也是动物福利的重要组成部分。（剩余29127字）