面向合成生物产业需求的生物制药工程设备课程教学改革

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中图分类号 TQ464;G642.0 文献标识码A 文章编号 1007-7731（2025）16-0127-05

DOI号 10.16377/j.cnki.issn1007-7731.2025.16.028

Abstract： To cultivate high-quality applied talents in synthetic biology，this studycarried outa systematic teaching reformon thecourseof Biopharmaceutical Engineering Equipment.Itanalyzed the current teaching situationof the course，including problems such as the dominanceof conventional lecture methods，the lack of practical teaching content，and the imperfection of the assessment system.By integrating the BOPPPS model and the double-teacher system to optimize the teaching content，a practical teaching method covering the whole process of gene operation， fermentation technology，separationandpurification，and preparation preparation was constructed.Moreover，a diversified evaluation system consisting of“usual performance + experimental report + basic assessment + （20 comprehensive assessment”was established.The reform has achieved remarkable results in the past 2 years： the scores ofstudents showanormal distribution，the proportionofstudents inthe2O21 grade who scored above9Opoints reached 7.4% ，which is an improvement compared with that before thereform，with zero failure，and the average score of teaching evaluation reached98.5 points.The research shows that the teaching reform of this course has strengthened students’systematic understanding of pharmaceutical engineering equipmentand improved theirabilityto analyze and solve practical problems.This paper provides a reference for the reform of similar biology courses.

Keywordssynthetic biology industry; Biopharmaceutical Engineering Equipment;teaching reform; industrial demand

生物制药工程设备课程整合了数学、物理学、化学、微生物学、化工原理和工程学等多个学科的知识体系，并依托基因工程、细胞工程、蛋白质工程技术，重点培养学生在生物药物研发与规模化生产中的工程设备应用能力。（剩余5549字）