肌少症与激素关系的研究进展

[Abstract]Sarcopeniaisageriatricsyndrome definedbythe gradualdecline inskeletalmuscle mass，strength，andfunctionality.Thetiologisitricate，cludingteactiosamongariouspysiologcalsystems，speiallendocinesteich secretesthegrowthhorone/insulin-likegrowthfactor-1axis，thyroidhormones，sexhormones（estrogenandtestosterone），sulin， vitaminD，andcortisol.Recentdataidicatestattseomonsareucaligtingseletalmusleproeinsthsis，tlie ellproliferatiometablicalacendifamatorsposs，allofchecatelylinkedtogiingndprogoo sarcopenia.Hormonereplacementtrerapyhasdemonstratedfcacyinenhancingsarcopenia.Thisreviewdelineatesthefunctinsof theaforementionedhomonesinthegnesisndprogresionofsrcopenia，intendingtofuishatheoreticalfoundationandresearch perspective for its prevention and treatment.

[Key words] Sarcopenia；Hormones；Elderly；Hormone replacement therapy

全球人口老龄化趋势日益严峻，应对老龄化相关疾病已成为重大公共卫生挑战。（剩余12039字）