膳食抗氧化指数与老年冠心病患者冠状动脉狭窄程度的关系

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[Abstract]ObjectiveToinvestigatetheasociationbetween dietaryantioxidant index（DAI）andthedegreeof coronary arterystenosisandprognosisinelderlypatientswithcoronaryheart disease.Methods2O6elderlypatientswhounderwentcoronary angiographyfromJanuary 2O22 January 2O24 were includedand divided ina CHD group（coronaryartery stenosis ⩾50% ，62 cases）and a control group （coronary artery stenosi <50% ，144 cases） according the degree of stenosis. The CHD group was further dividedinsingle（20cases），double（7cases）andthree（15cases）subgroupsacordingthenumberoflesions.Fodfrequency questionairewasusedcalculateteDAIscore，logisticregresionwasusedanalyzetheelatioshipbetweenDAIandmulti-vessel lesions，andthecoronaryheartdiseasegroup（57cases）wasfolowedupforamedianof12months，andtheindependentassociation betweenDAIandmajorcardiovascularadverseevents（MACE）wasanalyzedbyamultivariatelogisticregresionmodel.ResultsThe DAI score of the coronary heart disease group was lower than that of the control group （ P<0.05 ），and the DAI score decreased with the increasing number of coronary artery disease lesions （ P<0.05 ）.Multivariate logistic regression showed that a decreased DAI score was one of the independent risk facrs for multi-vessel lesions in patients with coronary heart disease（ P<0.05 ）．Follow-up showed that57patientswerefolowedup.ThelowertheDIbisectioninelderlypatientswithcoronaryhartdisease，thehighertheincidence of MACE.ThemultivaritelogisticregressonindicatedthattheDAscorewasaprotetivefacrafectingtheoccurrenceofMCE （ P<0.05 ）.Age， ⩾3 vessel lesions and low-density lipoprotein cholesterol were allindependent risk facrs affecting the occurrence of MACE （ P<0.05 ）.ConclusionTheDAI scoreof elderly patients with coronaryheart disease is significantly correlated with the degreofcoroaryterystenosisandpoorprognosis.LowDisnidepedntpredicrofulti-veseldiseaseadCEsges tingthatdietaryantioxidantcapacityaydelateprogresionoforonaryarterydiseasebyducingoxidativestress，rovidigaew basis for dietary intervention.

冠心病是一种因冠状动脉（供应心脏的血管）发生狭窄或堵塞，导致心肌缺血和供氧不足的疾病，尤其是在老年人中，其发病率和死亡率显著增加[1]。（剩余9740字）