超高效液相色谱-串联质谱法同时检测牛奶中7种杀虫剂残留

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【摘要】本研究以固相萃取技术作为样品前处理方法，通过超高效液相色谱-串联质谱对处理完的样品进行定性、定量检测，建立了同时测定牛奶中辛硫磷、敌敌畏、敌百虫、灭线磷、灭多威、杀线威和乙酰甲胺磷7种杀虫剂残留量的检测方法。结果表明，7种杀虫剂辛硫磷的检出限为2.0μg/L，定量限为5.0μg/L；杀线威的检出限为1.0μg/L，定量限为3.0μg/L；敌敌畏、敌百虫、灭线磷、灭多威和乙酰甲胺磷的检出限为0.5μg/L，定量限为2.0μg/L；在2.0～500.0μg/kg浓度范围内具有良好线性关系，R>0.999，平均回收率为70%～95%（RSD

【关键词】牛奶；杀虫剂；超高效液相色谱-串联质谱法；检测

【DOI编码】10.3969/j.issn.1674-4977.2024.02.001

Simultaneous Determination of 7 Insecticides in Milk by Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry

SU Weiyi， YANG Huijie， XU Lijia

（Liaoning Inspection，Examination & Certification Centre〔Liaoning Lnstitute forAgro-product Veterinary Drugs and Feed Control〕， Shenyang 110036， China）

Abstract： Study by using solid phase extraction technique as a pretreatment method， a tandem mass spectrometry on processed samples were detected qualitatively and quantitatively by ultra-high performance liquid chromatography analysis method to set up the milk of Phoxim， dichlorvos， trichlorfon， ethoprophos， methomyl， oxamyl and acephate.The detection limit of phoxim is 2.0μg/L， the quantitative limit of g/Lis 5.0μg/L， the detection limit oxamyl is 1.0μg/L， the quantitative limit of g/Lis 3.0μg/L， the detection limit for dichlorvos， trichlorfon， ethoprophos， methomyl， and acephate is 0.5μg/L， the quantitative limit of g/L is 2.0μg/L in the concentration of 2.0～500.0μg/L range and peak area were showed good linear relationship， R>0.999， the average recovery rate of 70%～95% （RSD

Keywords： milk； insecticide； UPLC-MS/MS； detection

杀虫剂污染是影响奶源安全性的因素之一。（剩余4295字）