冷光源蓝光照射治疗新生儿高胆红素血症后经皮测胆最佳测定时间的研究

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【摘要】目的 探讨冷光源蓝光照射治疗新生儿高胆红素血症后经皮测胆红素最佳测定时间。方法 选取2021年7月—2022年7月本院150例高胆红素血症患儿,随机分为5组,根据蓝光照射时间分组,分别是照射后第7h、8h、9h、10h、11h,每组各30例,对比分析各组及时间点对应的检测数据。结果 冷光源蓝光照射7h后经皮胆红素水平趋于平稳,经方差分析,光疗后第7h与第6h胆红素水平差异明显(P

【关键词】高胆红素血症;经皮测胆红素;冷光源蓝光照射

Study on the optimal time of percutaneous bile measurement after neonatal hyperbilirubinemia

SONG Shuhuan, LI Linlin, JING Baixia, WANG Guiying, CHANG Mingxiao

Neonatology Department, Liaocheng Second People’s Hospital, Liaocheng, Shandong 252600, China

【Abstract】Objective To determine the optimal time of bilirubin after neonatal hyperbilirubinemia. Methods 150 children with hyperbilirubinemia from July 2021 to July 2022 were selected, randomly divided into 5 groups, and grouped according to blue light irradiation time, namely 7,8,9,10 and 11 hours after irradiation, and 30 cases in each group. The test data of each group and time point were compared and analyzed. Results Percutaneous bilirubin levels leveled off 7h after blue light, and the difference of bilirubin levels between 7h and 6h after ANOVA (P

【Key Words】Hyperbilirubinemia; Percutaneous bilirubin; Blue light irradiation at cold light source

经过调查发现,足月新生儿中,黄疸发生率大约50%~60%,而早产儿中,黄疸率高达80%,这些黄疸多数为生理性黄疸,可以自然消退,但是存在少部分新生儿的高胆红素血症,很可能随着疾病的发展转变为胆红素脑病,重度核黄疸具有较高的死亡率,且后遗症发生率高,不仅增加了患儿的痛苦程度,也导致家属负担提升[1]。(剩余3983字)

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