喹硫平联合丙戊酸镁治疗男性双相情感障碍的临床疗效及安全性评价

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【摘要】目的：探讨联合以喹硫平与丙戊酸镁对双相情感障碍男性患者施治的价值。方法：试验对象选于2019年1月—2022年1月期间，在我院就医的双向情感障碍男性患者86例，以数字奇偶法均分为对照组与观察组，在施治期间提供丙戊酸镁与联合喹硫平施治，统计组间症状改善情况与用药反应差异性。结果：观察组狂躁症状及抑郁症状评分比对照组低（P

【关键词】双相情感障碍；男性；喹硫平；丙戊酸镁；施治效果；不良反应

Clinical efficacy and safety evaluation of quetiapine combined with magnesium valproate in the treatment of male bipolar disorder

WANG Juqin

Baiyin City， Gansu Province Huining County Tumen Xian Town health center， Baiyin， Gansu 730799， China

【Abstract】Objective： To explore the value of quetiapine combined with magnesium valproate in the treatment of male patients with bipolar disorder. Methods： The test subjects were selected from January 2019 to January 2022， 86 cases of male patients with bipolar disorder in our hospital were divided into control group and observation group by numerical even-odd method. Magnesium valproate and quetiapine combined treatment were provided during treatment， and the difference of symptom improvement and drug response between groups was statistically analyzed. Results： The scores of manic and depressive symptoms in the observation group were lower than those in the control group（P

【Key Words】Bipolar disorder； Men； Quetiapine flat； Magnesium valproate； Treatment effect； Adverse reactions

双相情感障碍作为临床常见精神疾病，具有较高发生率与复发率，在发病时患者主要交替存在抑郁与躁狂情绪，临床症状以情绪低落、思维迟缓、意识行为衰退等为主，当其出现躁狂情绪时，易表现出心境高涨、活动增多及思维奔放等症状[1]。（剩余3332字）