乙肝疫苗纳入免疫规划管理后对儿童乙肝表面抗原阳性率、血清学的影响

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【摘要】目的：分析乙肝疫苗纳入免疫规划管理后对儿童乙肝表面抗原阳性率、血清学的影响。方法：2002年1月前，乙肝疫苗未纳入儿童免疫规划管理，选择此阶段接诊的儿童39例，设定为对照组，另选取2018年1月—2020年1月接诊的儿童39例，设定为试验组，统计两组儿童乙肝表面抗原阳性率和血清学情况。结果：试验组全程接种率为100.00%，高于对照组89.74%（P

【关键词】乙肝；疫苗；抗原；免疫规划管理

Influence of hepatitis B vaccine inclusion in immunization program management on hepatitis B surface antigen positive rate and serology in children

HUANG Yonghong

Hong’an County Center for Disease Control and Prevention， Huanggang， Hubei 438400， China

【Abstract】Objective： To analyze the effect of hepatitis B vaccine on the positive rate and serology of hepatitis B surface antigen in children after being included in immunization program management. Methods： Before January 2002， hepatitis B vaccine was not included in the management of children’s immunization program， and 39 children admitted at this stage were selected as the control group. Another 39 children who were admitted from January 2018 to January 2020 were selected as the experimental group. The positive rate of hepatitis B surface antigen and the serological status of the two groups of children were compared. Results： The whole vaccination rate of the experimental group was 100.00%， which was 89.74% higher than that of the control group（P

【Key Words】Hepatitis B； Vaccine； Antigen； Immunization program management

乙型肝炎是一种常见传染性疾病，具体发病由乙肝病毒感染所致，传播方式较为多样，可通过血液、注射、母婴和性交等方式传播，其中母婴传播较多，儿童易感染此疾病，严重影响其健康情况[1-2]。（剩余3713字）