年龄相关性黄斑变性患者眼底图像分析与中医证型相关性研究

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[关键词]年龄相关性黄斑变性;中医证型;光学相干断层扫描;眼底荧光素血管造影;眼底辨证;中医目诊 [中图分类号]R276.7 [文献标志码]B [文章编号]doi:10.3969/j.issn.1674-070X.2025.06.013

Fundus image analysis in patients with age-related macular degeneration and its correlation with TCM patterns

LIU Zhimin', HU Zhuoyu², JIANG Jieyu², WANG Yusha²,HU Qi², PENG Qinghua2*, CHEN Xiangdong' 1.TheFirst Hospital of Hunan University of ChineseMedicine,Changsha,Hunan 41ooo7,China; 2. Hunan University of Chinese Medicine, Changsha, Hunan 41O208, China

[Abstract]ObjectiveToinvestigatethecorelationbetweenfundusimagecharacteristicsandTCMpattrnsinpatientswith age-relatedmaculardegeneration (AMD).MethodsFiftyhealthyindividualswereselectedasthehealthycontrolgroup;20OAMD patientsweredividedintothespleendeficiencywithdampnes group(SDDpattm),yindeficiencyleadingtofirehyperactivity group(YDFHpate),intertwinedpegmandbloodsasisgroup(PBSpe),anddfiiencyofteliverndidneygopLK pattem)basedonTCMpaterndiferentiation.GeneralinformationandpattrndatawererecordedOpticalcoherencetomography (OCT)wasusedtomeasurethechroidalandretinalthicknessinthemaculararea,andfundusfluoresceinangiography(A)and indocyaninegrenangiography(ICGA)wereusedtocheckthetypesofchoroidalneovascularization(CNV)inAMDpatientswith diferentTCMpatters.ResultsThecentralfovealthicknessof theAMDgroupwassignificantlygreaterthanthatofthehealthy group ( P

[Keywords]age-relatedmaculardegeneration;TCMpatern;opticalcoherencetomography;fundusfluoresceinangiography; fundus pattern differentiation; TCM eye diagnosis

年龄相关性黄斑变性(age-related macular de-generation,AMD)是引起全球老年人群失明的首要原因,主要表现为视网膜黄斑区的退化,从而导致中心视力下降和视觉功能障碍[1-2]。(剩余9119字)

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