基于“络病-扶阳"理论探讨桂枝附子汤对寒湿痹阻型痛风性关节炎的治疗

本文引用：.基于“络病-扶阳"理论探讨桂枝附子汤对寒湿痹阻型痛风性关节炎的治疗[]湖南中医药大学学报，2025，45（5）：945-949.

[关键词］痛风性关节炎；痹证；寒湿；桂枝附子汤；扶阳；络病 [中图分类号]R274.9 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.05.024

[Abstract]Goutyarthritis （GA）falls under the categoryofimpediment patern in Chinese medicine.Withthe deepening explorationofcolateraldiseasetheoryinChinesemedicine，theoccurrenceandprogressionofGAarecloselyrelatedto pathologicalchangesinthecollterals.Byanalyzingthepathogeesisofcold-dampnessimpedimenttypegoutyarthritis （CD-GA）at diferentstagesanditscharacteristicsicollteraldisease，tispaperdiscusesthediseasemechanismsintermsofthehidden pathogenicfactos，collteralobstruction，andcollteraldamage，highlightingatcollteralpathologyservesasthepatological basisofCD-GA，withcoldacompaniedbydampness-turbidityinvasionbeingthekeytrigerBasedonthetheoryof"collateral disease-fortifyingyang"，thisstudyelucidatesthetherapeuticefectsofGuizhiFuziDecoctionasacoreformulaforfortifyingyang andunblockingcollateralsintreatingCD-GA.Thefollowingmechanismsandtreatmentsareproposedasfollows.Asymptomatic hyperuricemiastage：Pathogenesisinvolvesdampnesslurkinginthecollteralstreatmentfocusesonforifingyangdispeling dampnessandunblockingolaterals;Acutegoutattacksage：Pathogensisinvolespathogenbructingeollteralsreatt prioritizes fortifying yang， unblocking collaterals， and alleviating pain; Chronic GA stage & gouty nephropathy stage： Pathogenesis involves pathogendamaginghecollteralstreatmentemphasizesforifngang，srengheninghalthyqi，andnourishngcater als.ThisstudyexploresthefoularationaleofGuizhiFuziDecoctionforCD-GAatdiferentstages，refinesitscompaibilityprinciples，and provides clinical application strategies for its use.

[Keywords]goutyarthritis;impedimentpatten;cold-dampness；GuiziFuziDecocion;fortfyingyang;colateraldisease

痛风性关节炎（goutyarthritis，GA）是一种代谢性疾病，是因尿酸代谢异常导致尿酸蓄积于血液中，长时间的高尿酸血症会导致尿酸盐结晶沉积于关节中，从而诱发的免疫炎症造成对关节的损伤，出现关节剧痛、肿胀等症状，严重者导致关节结构损伤，甚则残疾。（剩余7447字）