从“虚损生积”论治肝纤维化

中图分类号]R256.4 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.04.026

本文引用：.从“虚损生积"论治肝纤维化[J].中医药大学学报，2025，45（4）：753-756.

[Abstract]Liver fibrosis falsunder thecategoryof"abdominal masses"in Chinese medicine.Itismainlycausedbythe deficiencyofhalthyqi，stagnationofqiandbloodandteirccumulationintheliver.Byanalyzingtheexperienceofedical practitionerstroughouthistoryandcombiningwithclinicaloservations，ithasbeenfoundthatthabdominalmaesuringliver fibrosisiscloselyasociatedwiththedeficiencyofqi，blood，bodyfluids，andotheresentialsubstancesintheumanbody. "Deficiencyandimpairmentleadingtoabdominalmasses"isanimportantpathogenesisinthedevelopmentofliverfibrosisBased onclinicalandexperimentalresearch，modemTCMstudieshaveproposedthatthedeficiencyofhealthyqileadstobloodstasis obstructinginmeridiansandcolaterals，whichinturntrigersliverparenchymadamage.Basedonthepathogenesistheoryof "deficiencyandimpaimentleadingtoabdominal masses"，liverfibrosiscanbedividedintotheearlystage（liverdepresioand spleendeficiency），themiddlestage（liverandkidneyyindficiency）andthelatestage（stagnantbloodobstructingtheeridians） fortreatmentIntheearlystage，thefocusisonsoothingtheliverandstrengtheningthespleen;inthemiddlestage，thefocus ison nourishing the liver and kidney;and in the late stage，the focus is oncirculating bloodand transforming stasis.

[Keywords]liverfibrosis；deficiencyandimpairment leading toabdominal mases;；abdominal masss；stagedtreatment; deficiency of healthy qi

肝纤维化是肝组织损伤后，肝窦中的肝星状细胞被激活，进而导致细胞外基质异常沉积，肝组织被纤维结构取代的病理改变I。（剩余6241字）