厚朴饮片质量等级标准综合评分机制研究

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本文引用：．厚朴饮片质量等级标准综合评分机制研究[J].中医药大学学报，2025，45（4）：654-661.

关键词】厚朴；等级标准；主成分分析；正交偏最小二乘法判别分析；评分机制 [中图分类号]R284.1 [文献标志码]A [文章编号]doi：10.3969/j.issn.1674-070X.2025.04.010

[Abstract]Objective Toanalyze thequalityof Houpo Decoction-ready Medicines basedonvarious dataanalysissoftwares， andtoestablishacomprehensivescoringmechanism forthequality gradestandardof decoction-readymedicines.Methods Measure was madeon17batches of Houpo Decoction-ready Medicinesfromthe market fortheirappearancetraits，alcoholextract， ash，magnololiolsginagodatileposswaresedfoelaial data，combinedwithSIMCA14.1softwareforprincipalcomponentanalysisandorthogonalpartialleastsquaresdiscriminant analysis （OPLS-DA）toscreenthediferenceindexesafectingtheirquality.Thecomprehensivequalitygradeevaluationsystemof Houpo Decoction-ready Medicines was established using the analytic hierarchy process combined with K -valuecluster analysis. ResultsStatisticalanalysisofthecollectedindexdatafindsoutthatthediferenceindexesofHoupo（MagnoliaOffcinalis）were determined as L* ， b* ，magnolol，and extract.Houpo Decoction-ready Medicinescould be divided into three grades inaccordance withthetotalscoreswiththefrstgrade>11Opoints，thesecondgrade90-11Opoints，andthethirdgrade9Opoints.Conclusion Theestablishedcomprehensivescoring mechanismcanefectivelydistinguishthequalityofdiferentHoupoDecoction-ready Medicies and providescientific basis for the formulation ofquality grade standardsof decoction-ready medicines.

[Keywords]Houpo （Magnoliaoficinalis）;gradestandard;principalcomponentanalysis;orthogonal partial leastsquaresdiscriminant analysis; scoring mechanism

厚朴为木兰科植物厚朴Magnolia officinalisRehd.et Wils.或凹叶厚朴Magnoliaoffinalis Rehd.etWils.var.bilobaRehd.etWils.的干燥干皮、根皮及枝皮，具有燥湿消痰、下气除满的功效。（剩余9339字）