老年结直肠癌病人术后化疗期间营养状况与化疗不良反应的相关性

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AbstractOectiTvesitetutriialasadhureofmohaelaeddestosierlyattsi colorectacaegosoeratimotapdaltelatiosetstotalofrltsi colorectalcancerwhounderwentpostoperativechemotherapywereselected.Ageneralinformationsurveyform，thePatient-Generated SubjectiveGlobalAssessentGG）scalendacemotapdugaersereactoevaluatifowereusedtoesandiate duringthe5chemotherapycycles.Results：Duringthestudy，2caseswithdrewuetoospitaltransfer，3casesduetononcompliance withtheinvestigatiodaeetreattbdtUiately56patitsecudedinefalaalysisa ofPG-SGA scores before the 5 chemotherapy sessions showed statistically significant differences .Theoverall incidence of malnutrition was 80.13% 83.33% .As the course of treatment progresses，the incidence of moderate and severe malnutrition graduall increased. Asthetreatmentcourseprogsedteincideceandsverityofstrontestialractioandmyelosuppressngauallyicasda worsened.Among the gastrointestinal reactions，nausea had the highest incidence，accounting for 46.79% . In terms of bone marrow suppression，the incidence of early leukocyte and neutrophil decline was relatively higher，accounting for 32.69% and 32.05% respectively， whiletheincideneofateletandmoglbindeclinegraduallincreasedinthelaterstagesMalnuitionbeforethefirstceotapy session was correlated with vomiting，diarrhea，and leukopenia during chemotherapy ΔP<0.05 ）.Conclusions：Most elderly patientswith colorectalcanceralreadyhavemalnutritionbefortheirfirstpostoperativechemotherapysionAsthetreatmentcourseprogreete incidenceofoatedeautriualleasdedeitfmothlateddec graduallyincreaseandworsen.Malnutritioncanafectteocurrenceofcemotherapy-relatedadversereactions.Targetedintervetion plans should bedevelopedto improve thenutritional statusofpatientsand ensure thesmooth implementationofchemotherapy.

Keywordsthe elderly;colorectal cancer;chemotherapy;adverse reactions; malnutrition; correlation

关键词老年人；结直肠癌；化疗；不良反应；营养不良；相关性 doi：10.12102/j.issn.1009-6493.2025.17.017

结直肠癌属于我国高发恶性肿瘤之一。（剩余6664字）