重视意外胆囊癌的规范诊疗

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通信作者：，liuhbao@163.com（ORCID：0000-0003-0608-6522）

The standardized diagnosis and treatment of incidental galbladder carcinoma should be taken seriously

XUChang，JIN Cheng，LIU Houbao

DepartmentofliaySurgerystuteofliaryTractDiseases，ZongshanHospital，udan University，anghaiin

Correspondingauthor：LIU Houbao， liuhbao@163.com（ORCID：0000-0003-0608-6522）

Abstract：Incidental galbladder cancer（IGBC）refers togalbladder cancerdiscovered incidentally during pathological examinationaftercholecystectomyforbenigngalbladderdiseases，andcharacterizedbyahighrateofmisseddiagnosis before surgery，wide staging variability，and complex treatment decision-making，IGBC posesa significant challnge in biliarytract oncology.With reference to existingevidence，thisarticlesystematicallyreviews theepidemiology， pathogenesis，diagnosticstatus，and treatmentstrategiesofIGBC，analyzes existingbotlenecks indiagnosisandtreatment，and proposes thefuture prospects from the aspectsof preciseearly diagnosis，individualized treatment guidedby molecular subtyping，and establishmentofmultidisciplinarycolaboration models，inorderto provideareferenceforclinicalpractice and research.

Keywords：Gallbladder Neoplasms；Cholecystectomy；Diagnosis；Therapeutics

胆囊癌（gallbladdercancer，GBC）是胆道系统最常见的恶性肿瘤，因早期症状隐匿、缺乏特异性筛查手段，多数患者确诊时已属中晚期，5年生存率不足 10%[1] 。（剩余14527字）