磷酸三正丁酯对土壤典型无脊椎动物白符跳虫（Folsomiacandida)的毒性影响

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关键词：有机磷酸酯；土壤跳虫；基因表达；多代暴露；毒性效应及机理 中图分类号：X171.5；X53 文献标志码：A 文章编号：1672-2043（2025）09-2264-09 doi：10.11654/jaes.2024-0776

Abstract：Toevaluateeotentialfectsofommonorganophospatetersotypicalcolgicaleeptrinsoilthodelspcies springtails（Folsomiacandida）wasexposedtosoilcontaminatedwithtrin-butylphosphate（TnB）atenvionmentalconcentratiosof0， 0.01， 0.1， and 1mg⋅kg-1 .Responses of individual（growth，survival，and reproduction）and molecular（gene expression） level endpoints were measured. Results showed that after the first generational exposure，the body weight and reproduction of springtails were significantly and abnormally increased in the 0.1 mg·kg-1 treatment group，and 816 genes showed diferential expression（the most were upregulated）.Pathwayssuchasextracelularmatrix（ECM）-receptorinteractionandsteroidhormonebiosynthesisweresignificantly enhanced.After the fifth-generational exposure in the 0.1mg⋅kg-1 treatment，the body weight and reproduction were significantly decreased，and38gnessoeddiferentialepresson（theosredoweguated）.Gutathioemetabolismndtheabove mentionedtwoathasereignificantlybited，moreover，rbohdrateetabolismelatedpathays（glyolysis/glucois pyruvatemetabolism，andcitricacidcycle）weresignficantlydisrupted.ThisstudyhasshownthatthecologicaltoxicityofTBPto springtailsatevromentallrelevantlowoncentrationsaoteigored.Contiuousultineratioallong-texposuretoxiciy testing can provide more basis for toxicity risk assessment of pollutants. Keywords：organophosphateeters;soilspringtails;geneexpression;multigenerationalexposure;toxicityefectsandmaiss

有机磷酸酯（OPEs）是溴系阻燃剂的替代品，在家具、建筑材料、塑料制品和电子产品等各类产品中被广泛用作阻燃剂或增塑剂]。（剩余15002字）