依达拉奉右莰醇联合阿替普酶治疗对急性缺血性脑卒中患者脑血流动力学状态、神经功能及预后的影响

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Effect of Edaravone and Dextrorphan Combined with Alteplase on Cerebral Hemodynamic Status， Neurological Function and Prognosis in Patients with Acute Ischemic Stroke

YANG Haiping

Departmentof Neurology，Ji'an County People'sHospital，Ji'an 3431Oo，Jiangxi，China）

Abstract：Oectiestigatetraodetadieplaserebalmodatuolcal functionadprogosisiatitsitcuteschcrokeMtodsAtotalof6Opatietsituteheicrkedmitedtoart ofNeurologytesspialfJuareeedseaheogo numbertablemethod，theyweredividedintocontrolgroupandsudygoupwith3Opatientsineachgroup.Theontrolgoupastreatedwith intraveoushrombolysisithleplasendtdoupraeditravonddetroaeoocetradlutioosis fthecontrolouhtfeurolalcio（orCore）ebraldcauile resistance index，mean blood flow velocity），inflammatory factor levels [tumor necrosis factor α （TNF-α），interleukin-6 （IL-6），interleukin-2 （IL-2）] andvascularrecaaliatioatewerecomparedetwetetooupsResultsThefectiveateoftreatmentinthesudygoupasighrthan that in the control group （ P<0 . 0 5 ） .Aftertreatment，the neurological function of the study group was beter than that of the control group P<0 . 0 5 ） .The pulsatlityindedsistaedeofteudyouperelowrantooftotroloupileaveralodfoweoitashigr than that of the control group .Thelevels of inflammatory factors inthestudy group were lower than thosein the control group，and the vascular recanalization rate was higher than that in the control group（ .Conclusion Edaravone and dextrose combined with alteplase is effetivintereamentofintsithcuteheictrokeichanmproeterurologcalfuctiondcebralmodaicatus reducetheinfammatoryesponseofpatients，andimprovetheascularrecanalizationrateofpatints.Ithasxcellntclinicalvalue.

Keywords：dadrool；epsutecalrcebalaec

急性缺血性脑卒中多因脑内血液循环突发障碍而发生堵塞、局部缺血缺氧，具起病急骤、病情进展速度快、致残率高、致死率高等明显特点，需立即入院实施抢救治疗，保障患者生命安全1。（剩余6717字）