丁苯酞联合高频重复经颅磁刺激对脑梗死后 吞咽障碍的影响

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Effect of Butylphthalide Combined with High-frequency Repetitive Transcranial Magnetic StimulationonDysphagiaafter Cerebral Infarction/LIMingyu,LONGChuangang.//Medical Innovation of China,2025,22(20):116-120

[Abstract]Objective: To evaluate the effcts of Butylphthalide combined with high-frequency repetitive transcranial magnetic stimulation (HF-rTMS)onpatients with dysphagiaafter incerebral infarction.Method:A total of 100 patients withdysphagiaafterincerebral infarctionadmited toJiujiangNO.1People's HospitalfromDecember 2022 to December 2O24 were retrospectively selected.According to diferent treatment plans,they were divided nto control group of 5O cases and observation group of 5O cases.The control group was treated with Butylphthalide,and the observation group was treated with HF-rTMS in addition to the treatment provided by the control group.The treatment efficacy,swallowing function [video fluoroscopic swallowing study (VFS),modified Mann assessmentof swallowing ability (MMASA)],oral feeding ability[function oral intake scale (FOIS)], and qualityof life[swallowingquality of life (SWAL-QOL)] between the two groups were compared.Result: The treatment effcacy rate in the observation group was higher than thatof the control group,after treatment,the VFSS,MMASA,FOISand SWALQOL scores of both groups were higher than those before treatment,and the VFSS,MMASA,FOIS and SWAL-QOL scores of the observation group were higher than those of the control group ( P <0.05).Conclusion:Butylphthalide combined with HF-rTMS caneffctively treat patients with dysphagia after cerebral infarction can improve swallowing function and transoral feeding ability,and enhance their quality of life.

[KeyWords] ButylphthalideHigh-frequency repetitive transcranial magnetic stimulation Dysphagia 'erebral infarction Swallowing function

First-author's addres: Department of Neurology,Jiujiang NO.1 People's Hospital, Jiujiang 332000, China

doi: 10.3969/j.issn.1674-4985.2025.20.027

脑梗死是全球范围内导致死亡和残疾的主要病因之一[]。(剩余6645字)

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