美沙酮、抗病毒治疗联合应用于HIV感染的临床效果分析

【摘要】目的：分析对于HIV感染患者合用美沙酮及抗病毒治疗的临床价值。方法：抽取2019年1月—2020年1月本院74例HIV感染患者，随机数字表法分组，对照组为抗病毒治疗，同期观察组则合用美沙酮及抗病毒治疗，比较两组治疗后的病毒载量以及治疗前后的CD4+水平。结果：治疗后，观察组病毒载量0.05）；治疗前，两组的CD4+水平均较低且组间对比差异不大（P>0.05），治疗24周、48周，观察组CD4+水平较对照组更高（P

【关键词】HIV感染；美沙酮；抗病毒治疗；价值

Clinical effect analysis of combined methadone and antiviral therapy in HIV infection

WU Guilian

People’s Hospital of Golmud City，Qinghai， Golmud， Qinghai 816000， China

【Abstract】Objective：To analyze the clinical value of combined methadone and antiviral therapy for HIV infected patients.Methods：A total of 74 HIV infected patients in our hospital from January 2019 to January 2020 were selected and divided into two groups by random number table method.The control group was given antiviral therapy，and the observation group was given methadone and antiviral therapy at the same time. The viral load after treatment and CD4+ level before and after treatment were compared between the two groups.Results：After treatment，the proportion of viral load0.05；Before treatment，the CD4+ levels of the two groups were lower，and there was little difference between the two groups（P>0.05），and the level of CD4+ in the observation group after 24 and 48 weeks of treatment was higher than that in the control group（P

【Key Words】HIV infection； Methadone； Antiviral therapy； Value

人類免疫缺陷病毒（HIV）感染是诱发艾滋病的根本原因，HIV感染者未进行规范化的治疗，随着病情进展容易诱发各类重度感染甚至恶性肿瘤，使得患者的死亡率提升。（剩余3408字）