青年乳腺癌与绝经后乳腺癌的病理特点比较分析

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【摘要】目的：探析青年乳腺癌与绝经后乳腺癌的病理特点。方法：选择2018年10月—2021年9月在本院接受诊治的22例青年乳腺癌患者（研究组）与21例绝经后乳腺癌患者（对照组）为研究对象。评估两组患者免疫组化结果、组织学分级与病理分期以及肿瘤组织分子亚型。结果：研究组患者HER-2阳性率与Ki-67高表达率、病理Ⅲ期占比以及三阴型占比高于对照组，PR与ER阳性率、组织学Ⅰ级占比、病理Ⅱ期占比以及Luminal A型占比低于对照组（P

【关键词】青年乳腺癌；绝经后乳腺癌；病理特点

Comparative analysis of pathological features between young breast cancer and postmenopausal breast cancer

HUI Hongwei

Department of Laboratory，Xi’an Baqiao District Maternal and Child Health Care Family Planning Service Center， Xi’an， Shaanxi 710038， China

【Abstract】Objective：To investigate the pathological characteristics of young breast cancer and postmenopausal breast cancer.Methods：22 young breast cancer patients（study group）and 21 postmenopausal breast cancer patients（control group）were selected from October 2018 to September 2021.The results of immunohistochemistry，histological grade，pathological stage and molecular subtype of tumor tissue between the two groups were evaluated.Results：The positive rate of HER-2 and the high expression rate of Ki-67，the proportion of pathological phaseⅢ and triple negative type in the study group were higher than those in the control group，and the positive rate of PR and ER，the proportion of histological grade I，the proportion of pathological phase II and the proportion of Luminal type A in the study group were lower than those in the control group（P

【Key Words】Young breast cancer； Postmenopausal breast cancer； Pathological features

乳腺癌在女性恶性肿瘤中发病率与致死率居首位，且年龄发病率存在双峰发布特征，随女性生活方式改变，该疾病发病率呈现年轻化趋势，流行病学相关研究显示，不同年龄阶段该疾病患者恶性程度存在一定差异，因此，了解不同年龄阶段该疾病患者病理特征对临床采取有效治疗具有重要意义[1]。（剩余2390字）