铁死亡中铁稳态在阿尔茨海默病的研究进展

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Research progress of the role of iron homeostasis in ferroptosis in Alzheimer's disease

Luo Chenliang1，²，Wu Guiyou1，Li Zhenzhong²，Huang Zhongshi³ ** （204号 1 Graduate School，Guangxi UniversityofChinese Medicine，Nanning5302oo;ScholofPharmacy，YoujiangMedical Universityfor Nationalities，Baise533ooo；ScholofBasic Medicine，Youjiang MedicalUniversityforNationalities，Baise533000 **Corresponding author：Huang Zhongshi，email：hzs1004@ 163.com

[Abstract]Feroptosisisadticttypeofcellardemiefrequentlyidentifedinthecerebraltissuesofindividualsflite withAlzheimerssease（AD）Itontributestothdvancementofseveraldsorders，ncudingdementiaalignancies，doste porosis，ithtdieeiallprdsoatediitisiiftldiesasaedis orderedironeosisisalisoosisoiseialialusfo ing mitochondialenergyproduction，synthesizingmyelinandneurotransmiters，andfacilitatingotherfundamentalphysiologicalfunc tions.Thisaticleofesanetesiveanalysisoftheiteractionsaongaycriticalelementsrelatedtoironomeostasis，fotosis， and the common pathogenic mechanisms linked to Alzheimer's disease （AD）.

[Keywords] Alzheimer's disease，Ferroptosis，Iron homeostasis，Iron homeostasis regulators

铁死亡是一种铁依赖性的细胞死亡形式，它在形态学、生物化学、基因和蛋白表达水平上，均不同于其他形式的细胞死亡[]。（剩余15822字）