睡眠障碍与慢性疾病关系的研究进展

Recent advances in understanding the link between sleep disorders and chronic diseases

Li Xu1，2 ，Li Jinke²，Hou Liming²，Wang Xiaoming² * 1Xian Medical Colege，Xi'an0o68;²DepartmentofGeriatrics，Xijing Hospital，AirForce Medical University，Xi'an710032 ** Corresponding author： Wang Xiaoming，email： xmwang@ fmmu.edu. cn

[Abstract]SleepisafundamentalphysiologicalnecessitythatplaysacrucialroleinmaintainingoverallhalthSleepdisorders，agroupofnditostatdsuptoalsleepattseprentaprevaentcliicalisse.Isuto-restoiesleep canmpairphyicalognitive，socialndotioalfunctios，gnificantlducingoverallalthndualityoflife.Esie searchhas establishdastrongassociatiobetweensleedisordersandtheonsetandprogessonofvariouschronicdiseases，cluding cardiovasculardisease，iabetes，besity，andneurologicaldisorders.Keypathologicalmechanismslinkingslepdisorderstoonc diseasesincludeautonomicnervous system dysfunction，oxidative stress，endothelial dysfunction，andbrainfunctionabnomalities. This reviewsummarzesrecentadvances inunderstanding therelationshipbetween sleepdisordersandchronicdiseases，aiming topro vide insights for the prevention and management of chronic health conditions.

[Key Words]Sleep disorder;Cardiovascular system；Obesity；Diabetes melitus；Nervous system

睡眠作为人体必需的生理需求，在调节身心健康和机体功能方面发挥重要作用，特别是与机体的免疫、代谢功能密切相关。（剩余9075字）