赣州市某高校一起结核病聚集性疫情调查分析

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关键词：结核病；学校；聚集性疫情；重组结核杆菌融合蛋白

中图分类号：R181.8+1文献标志码：A文章编号：1001-5779（2025）05-0461-05

DOI：10.3969/j.issn. 1001-5779.2025.05.009

Abstract：Objective：Toanalyzethe investigationand handlingofatuberculosis clusteroutbreak inauniversityin Ganzhoufrom April to May 2O23，soas toprovideabasis fordealing with similar epidemics inthe future.Methods： We describedand statisticallyanalyzed theoccurrenceanddevelopmentof theepidemicandthemeasures todeal with it，the epidemiological investigationofthecase，thescreening resultsofclosecontactsand generalcontacts.Results：Atotalof 3casesof tuberculosis weredetected.Theyweredistributed inthesameclassanddormitory.Inthescreening of close contacts，theEC positive/strong positive rateof the case in the class was22.86%（8/35）and thatof otherclasses was （204号 1.79% （ 1/56 ），and the difference between the two was statistically significant （ χ2 =8.497，P=0.004）.The EC positive/ strong positive rate among close contacts was 9. 78 % （9/92），and the EC positive/strong positive rate among general contacts was 1.72% （ 1/58 ），which was 5.69 times that of general contacts，but the diference was not statistically significant （ χ2=2.530，P=0.112 .Conclusion：The first case was studying and living in school for a long time，which wasthemainreason fortheoccurrenceofclusteroutbreaks.Itis necessaryto strengthen thehealtheducationof teachers andstudents，and improve theawareness of tuberculosis preventionandcontrolamong teachersand students；theuniversity shouldimplementtheinvestigationof thecausesofabsenceduetoillnessand detect suspected casesof tuberculosisas early as possible.

Key Words： Tuberculosis； School； Cluster outbreaks；Recombinant mycobacterium tuberculosis fusion protein

2023年4月10日，赣州市某结核病定点医疗机构报告1例病原学阳性学生肺结核患者，为赣州市某高校A学院1班学生，当地疾控机构随即对该病例进行流行病学调查和密切接触者筛查等处置工作，发现2例与指示病例有流行病学关联的学生肺结核患者，整个处置过程严格按照《中国学校结核病防控指南（2020年版）》要求进行，在病预防控制中心、学校等多方共同努力下，该起疫情得到有效控制。（剩余5824字）