雷火灸联合中药治疗对冻融胚胎移植妊娠结局的影响

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关键词：雷火灸；子宫内膜容受性；冻融胚胎移植；临床妊娠率

中图分类号：R715文献标志码：A 文章编号：1001-5779（2025）05-0448-05

DOI：10.3969/j.issn.1001-5779.2025.05.006

Abstract：Objective：To explore theeffectofThunder-fire Moxibustioncombinedwith Chinese medicineon the assisted reproductiveoutcomes of patientsundergoing frozen-thawed embryo transfer.Methods：Aretrospective analysis was conductedontheclinicaldataof8O infertilepatientswhounderwentfrozen-thawedembryo transfertreatment inthe Departmentof Reproductive Medicine at Xinyu Maternal and Child Health Hospital from January2O2Oto December 2023.The patients were divided into two groups based on the treatmentreceived： the experimental group（40cases）and the control group （40 cases）.The control groupunderwent endometrial preparationusing a hormone replacement regimen， whiletheexperimentalgroupreceivedThunder-fireMoxibustioncombinedwithidney-tonifyingChinesemedicinereatment onthebasisofhormonereplacementtherapy.Thegeneralcharacteristicsofthepatients，endometrial thickness ontheday of embryo transfer，and pregnancyoutcomes were analyzed between the two groups.Results：There were no statistically significantdiffrences inheaverageage，infertilityduration，bodymassindex，andbasalhormonelevelsofthepatients and their spouses between the two groups （ P>0.05 ）.Similarly，there were no statistically significant differences in the quality and number of transplanted embryos （ P>0.05 ）. The endometrial thickness in the experimental group on the day of transplantationwassignificantlyincreasedcomparedwiththecontrol group，withastatisticallsignificantdiference 1 （P=0.003） . The embryo implantation rate 65.9% ）and clinical pregnancy rate（ 70% ） in the experimental group were both higher than those in the control group，with embryo implantation rate （42.5% ）and clinical pregnancy rate （47.5%） ，and thedifferenceswere statistically significant（ P<0.05， .Thebiochemical pregnancy ratein theexperimental group（ 5% ）was much lower than that in the control group（ 20% ），withastatisticallysignificantdifference（ P<0.05 ） Conclusion：The treatmentofThunder-fire Moxibustioncombinedwith kidney-tonifying traditionalChinesemedicinecan increaseendometrial thickness，improveendometrial morphology，therebyenhancing endometrialreceptivity，and improvingthe embryo implantationrateand clinical pregnancyrate in patients undergoing frozen embryo transfer. KeyWords：Thunder-fire Moxibustion;Endometrialreceptivity；Frozen-thawedembryotansfer;Clinicalpregnancyrate

当前不孕不育的发病率逐年上升，据世界卫生组织统计，在欧美发达国家，每6对夫妇中就有1对夫妇面临不孕不育的困扰[1，而辅助生殖技术已成为解决不孕不育问题的主要途径。（剩余7072字）