牙髓干细胞在牙槽骨再生中的成骨作用及影响因素

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[中图分类号]R78 [文献标志码]A [doi] 10.7518/gjkq.2026201

[Abstract]Dentalpulp stemcells （DPSCs）have potential forself-renewalanddierentiation into various celltypes. Theycan be transplanted into the defect areaof the alveolarbone to induce their differentiation intoosteoblasts，thereby promoting the regeneration and reconstructionof thealveolar bone.This study reviews the osteogenic abilityofDPSCs in alveolarboneregenerationandthefactorsthatinfluencetheirosteogenicability.Thechallengesfacedintheclinicalapplication of DPSCs are analyzed to provide insights into the basic research and clinical application of DPSCs for repairing the alveolar bone.

[Key words] dental pulp stem cell；alveolar bone;bone defect；bone regeneration

牙髓干细胞（dental pulp stem cell，DPSC） 来源于外胚层，起源于迁移的神经嵴细胞，能够 表达多种间充质干细胞（mesenchymal stemcell，MSC）标志物，例如CD13、CD29、CD44、CD73等]。（剩余19215字）