机械敏感性受体在正畸牙移动中的研究进展

打开文本图片集

[中图分类号] R783.5 [文献标志码]A [doi] 10.7518/gjkq.2026203

Researchprogressof mechanosensitivereceptors inorthodontictoothmovement

SuXuanchen²，DongYijia，hiYuwen，LiuYalil，3

1.SchooloftolgyigicalUeityia;Kytorl gy，Kunmingia3.eptofodoicstmtolgcalHositalAfatedtoKumingeicalUeity Kunming650106，China

Supported by：National Natural ScienceFoundationofChina （31860326，82460194）;Joint Fundof Yunnan Provincial ScienceandTechnologyOfceandKunmingMedicalUniversity（2O23oAYo7oo-010）;NationalCollegeStudentInno vationand Entrepreneurship TrainingProgram （202310678040）

Correspondence：LiuYali，Email：liuyalizu@163.com

[Abstract]Inthe process oforthodontic tooth movement，periodontal tissue relatedcelsperceiveand respondtomechanicalstimulation，andtheperiodontal tssueadaptivereconstructionoccurs，andfinallthetoothmovementisrealized. Severalmechanosensitivereceptors，suchasPiezol，transientreceptorpotentialvaniloid，primaryciliaand integrin，ave ben found toplayarole inorthodontic tooth movement，butthe specific mechanisms remain tobefurther elucidated. In this paper，the mechanismofmechanosensitivereceptors inorthodontic tooth movementinrecentyearsandtheirpossible interaction were summarized，inorder to providereference for the studyofthemechanobiology mechanismoforthodontic tooth movement.

[Key words] orthodontic tooth movement; mechanosensitive receptor; mechanobiology

牙齿-牙周膜-牙槽骨复合体始终处于一个复杂的生物力学平衡，而正畸治疗通过施加正畸力打破这一动态平衡，最终实现正畸牙移动（ortho-dontictoothmovement，OTM）[1]。（剩余19934字）