植入前多基因检测的伦理问题探究

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[中图分类号]R-052 [文献标志码]A [文章编号]1001-8565（2025）11-1425-06

DOI：10.12026/j.issn.1001-8565.2025.11.07

Abstract： Preimplantation polygenic testing，as a frontier technology in assisted reproduction，provides a new way to prevent genetic diseases and reduce birth defects.However，it may also trigger a series of ethical issues. Combined with the research progressof preimplantation polygenic testing，this paper explored the ethical sues that maybe caused bythis technology，including the risksand uncertain benefits forfuture ofspring and thechallenges of informed consent，the dilemmas of autonomous decision-making and genetic responsibilityof prospective parents，as wellas socialriskssuchasthedistortionof theviewoflifeandhealth inequities.Giventhe technicalsafetyissuesand ethical callnges posed by preimplantation polygenic testing，it was proposed to revise the regulations related to preimplantation genetic testing，as well as improve the ethical review of preimplantation polygenic testing，genetic counselng services，and public education on genetic science and genetic ethics.These ethical countermeasures aim to prevent and mitigate risks and ensure that technology truly benefits human society.

Keywords： preimplantation genetic testing；polygenic risk score；polygenic disease

0 引言

20世纪80年代植人前基因检测（preimplantationgenetictesting，PGT）诞生。（剩余10812字）