运动联合健康教育对肥胖儿童炎症因子及NO、ET的影响

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Effects of Exercise Combined with Health Education on Inflammatory Factors and NO，ET in Obese Children

WANGRui，LINingchuan，ZHAO Yue，HE Liu，WANGQihang （PE college，Yangzhou University，Yangzhou Jiangsu，，China.）

Abstract：Objective：To explore theefectsof exercise combinedwith health educationonnitric oxide（NO）and endothelin（ET）inobesechildren，andtoprovidereferencesforchildren'sobesity.Method：Atotalof47obesechildren ingrades3and4ofJiangWangCentralPrimarySchoolinYangzhouCitywereselectedandrandomlydivided into control group（C），obesitycontrolgroup （FC），exercisegroup（E），andhealtheducationgroup（H），exercisecombined withhealtheducationgroup（HE），implementa24-week exercisecombinedwithhealtheducationintervention，inwhich theformof exercise is mainlyaerobicexercisecombined with somestrength exercises.The subjects'blood lipids， MCP-1，MIP-1α，hs-CRP，NO，ETandotherindicators weredetectedwithin24hoursbforethestartoftheexperiment andafter24weeksof intervention.Results：After24weeksof intervention，the BMIof Hincreased significantly （P<0.05） ，and IP-1α increased significantly （P<0.01 ；EBMI， Fat% ，TG，LDL-C/HDL-C，MCP-1，MIP-1α，hs-CRP，ET decreased ignificantly （P<0.05） ；LDL-Clevelsdecreased significantly （P<0.01） ，NOincreased significantly （P<0.05） ， BMI， Fat% ，TC，LDL-C，MCP-1，hs-CRPdecreased significantly （P<0.01）， ，TG，LDL-C/HDL-C，MIP-1α，ETdecreased significantly （P<0.05） ，andNO increased significantly （P<0.05） ；Compared with the obesity control group，the indexes oftheEgroupandtheHEineachgroupweresignificantlyimproved，buttheoveralleffctoftheHEwasbetterthan thatoftheE.Conclusions：exercisecombined with health educationcanbeter improve thechronic inflammationcausedby thedisorderofbloodlipidmetabolisminobesechildren，andrebuildthebalanceofvascularendothelialandvasoconstrictor factors.Keywords：erobicexercise，healthducation，obesechildren，nflammatoryfactors，dothelialfuction.

Key words：Aerobic exercise;Health education;Obese children;Inflammatory factors;Endothelial function

中图分类号：G804.22文献标识码：A

2017年5月11日，北京大学公共卫生学院与中国营养学会联合发布的《中国儿童肥胖报告》指出，我国7岁及以上学龄儿童中已有约3496万人处于超重或肥胖状态。（剩余10248字）