避实击虚法论治原发性干燥综合征合并肺间质性病变

【中图分类号】R249.2/.7 【文献标志码】A 【文章编号】1007-8517（2025）14-0091-05

DOI： 10.3969/j .issn.1007-8517.2025.14. zgmzmjyyzz202514018

TheStrategy of Addressing the UnderlyingDeficiencies While avoiding Exacerbation in the Treatment of Primary Sjogren's Syndrome Complicated by Interstitial Lung Disease

CHENG Xin1SONG Jiajia1CHEN Xing1PENG Jiehao1HUANG Yingling1WANGWeitao1 PENG Tao 1，2 “ 1.Shanxi University of Traditional Chinese Medicine，Taiyuan O3OO24，China; 2.Affiliated Integrated Traditional ChineseandWestern Medicine Hospital of Shanxi Universityof Traditional Chinese Medicine，Taiyuan O30013，China

Abstract：PrimarySjogren’ssyndromeisachronicinflammatoryautoimmunedisease，with interstitiallungdiseasebeing oneof its mostcommonseverecomplications，boastingahighincidenceandortalityrate.Curently，WesternmedicieoferslimitedthrapeuticeffcacyandomeswithsubstantialideefectsforthisconditionProfesorPengdiscoveredthatthisdiseaseisoftencaracter izedbyQi-Yindeficiencyasitscore，whichpersiststhroughoutthecourseofthedisease.WhenQi-Yinisdeficient，thechanels andcollteralsbcomeobstructed，leadingtotheaumulationofplegmandblodstasisovertime.Theavoiding themanifestations andatackingtherooapproachavoidsthemanifestationsofphlegmandbloodstasisndtargetstherootofQi-YindeficiencyThe maintreatmentprincipleis tosupplementQi-Yin，withoutfocusingondryingphlegmoreliminatingbloodstasis.Byrestoringphysi logical functionsandresistingtheprogresionofthedisease，thepatient’sconditioncanbeimprovedand progosisimproved.

Key words：Sjogren Syndrome；Interstitial Lung Disease；Clinical Approach；Medical Cases

原发性干燥综合征（primary sjogren syndrome，pSS）是一种常见的以外分泌腺淋巴细胞浸润为特征的慢性炎症性自身免疫性疾病，总体患病率为0.3%～1% ，临床表现多以口眼干燥、腮腺肿胀为主，往往伴有多器官、多系统损伤，呼吸系统是pSS常受累的系统之一，主要表现为肺间质病变（interstitial lungdisease，ILD），约有 22% 的pSS患者会继发 ILD[1] 。（剩余6775字）